OPDIVO 100 MG / 10 ML ( NIVOLUMAB ) FOR INTRAVENOUS INFUSION USE 10 ML VIAL

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decreased sex drive, irritability, or forgetfulness

Kidney problems — Things to look out for may include:

 

decrease in your amount of urine

blood in your urine

swelling of your ankles

loss of appetite

Skin problems — Things to look out for may include:

 

rash

itching

skin blistering or peeling

swollen lymph nodes

painful sores or ulcers in the mouth or nose, throat, or genital area

fever or flu-like symptoms

Eye problems — Things to look out for may include:

 

blurry vision, double vision, or other vision problems

eye pain or redness

pain in muscles, bones and joints

constipation

decreased appetite

rash

vomiting

numbness, pain, tingling, or burning in your hands and feet

The most common side effects of OPDIVO when used in combination with cabozantinib include:

 

diarrhea

feeling tired or weak

liver problems

rash, redness, pain, swelling, or blisters on the palms of your hands or soles of your feet

mouth sores

rash

high blood pressure

low thyroid hormone levels

pain in muscles, bones, and joints

decreased appetite

nausea

change in the sense of taste

stomach-area (abdominal) pain

cough

upper respiratory tract infection

The most common side effects of OPDIVO when used in combination with fluoropyrimidine- and platinum-containing chemotherapy include:

 

nausea

numbness, pain, tingling, or burning in your hands or feet

decreased appetite

feeling tired

constipation

mouth sores

diarrhea

vomiting

stomach-area (abdominal) pain

pain in muscles, bones, and joints

These are not all the possible side effects. Talk to your healthcare team or pharmacist for more information. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088.

 

What should I discuss with my healthcare team before receiving OPDIVO or YERVOY?

 

Tell your healthcare provider about all your medical conditions, including if you:

 

have immune system problems such as Crohn’s disease, ulcerative colitis, or lupus

have received an organ transplant, including corneal transplant

have received or plan to receive a stem cell transplant that uses donor stem cells (allogeneic)

have received radiation treatment to your chest area in the past and have received other medicines that are like OPDIVO

have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome

are pregnant or plan to become pregnant. OPDIVO and YERVOY can harm your unborn baby.

are breastfeeding or plan to breastfeed. It is not known if OPDIVO or YERVOY passes into your breast milk. Do not breastfeed during treatment and for 5 months after your last dose of OPDIVO or YERVOY.

Females who are able to become pregnant:

 

Your healthcare provider should do a pregnancy test before you start receiving OPDIVO or YERVOY.

 

You should use an effective method of birth control during your treatment and for 5 months after the last dose of OPDIVO or YERVOY. Talk to your healthcare provider about birth control methods that you can use during this time.

Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with OPDIVO or YERVOY. You or your healthcare provider should contact Uk-online-pharmacy as soon as you become aware of a pregnancy.

Tell your healthcare provider about all the medicines you take, including:

 

prescription medicines

over-the-counter medicines

vitamins

herbal supplements