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Generic name: Azithromycin
Brand name: Zithromax - Zitromax - Azithromycin
Zithromax is an antibiotic related to erythromycin. It
is prescribed for adults to treat certain mild to moderate skin infections;
upper and lower respiratory tract infections, including pharyngitis (strep
throat), tonsillitis, worsening of chronic
obstructive pulmonary disease,
and pneumonia; sexually transmitted infections of the cervix or urinary
tract; and genital ulcer disease in men. In children, Zithromax is used
to treat middle ear infection, pneumonia, tonsillitis, and strep throat

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Most important fact about Zithromax
There is a possibility of rare but very serious reactions
to Zithromax, including angioedema (swelling of the face, lips, and neck
that impedes speaking, swallowing, and breathing), anaphylaxis (a violent,
even fatal allergic reaction), and serious skin diseases. If you develop
these symptoms, stop taking Zithromax and call your doctor immediately.
How should you take Zithromax ?
Take Zithromax capsules at least 1 hour before or 2 hours
after a meal. Zithromax tablets and oral suspension can be taken with
or without food. Do not take any form with an antacid that contains aluminum
or magnesium, such as Di-Gel, Gelusil, Maalox, and others.
If you are using single-dose packets of Zithromax powder
for oral suspension, mix the entire contents of each packet with 2 ounces
of water, drink immediately, then add an additional 2 ounces of water,
mix again, and drink to make sure you've taken the entire dose. When giving
the pediatric suspension, shake the bottle thoroughly before each use
and measure the dose with the supplied calibrated dropper. Use the pediatric
suspension within 10 days and throw out any that remains.
Be sure to take all the Zithromax prescribed. If you stop
taking Zithromax too soon, some germs may survive and the illness may
return.
If you miss a dose of Zithromax
Take the forgotten dose of Zithromax as soon as you remember.
If you don't remember until the next day, skip the dose and go back to
your regular schedule. Never try to "catch up" by doubling the
dose.
Storage instructions for Zithromax
Zithromax should be stored at room temperature.
What side effects may occur when taking Zithromax
?
Side effects cannot be anticipated. If any develop or
change in intensity, inform your doctor as soon as possible. Only your
doctor can determine if it is safe for you to continue taking Zithromax.
More common side effects may when taking Zithromax
include:
Abdominal pain, diarrhea or loose stools, nausea or vomiting
Less common side effects may when taking Zithromax
include:
Blood in the stools, chest pain, dizziness, drowsiness,
fatigue, gas, headache, heart palpitations, indigestion, itching, jaundice
(yellowing of the skin and the whites of the eyes), kidney infection,
light sensitivity, rash, severe allergic reaction including swelling (as
in hives), vaginal inflammation, vertigo, yeast infection
Other uncommon side effects sometimes seen in
children with Zithromax include:
Agitation, constipation, cough, facial swelling, feeling of illness, fever,
fungal infection, insomnia, loss of appetite, nervousness, overactivity,
pinkeye, runny nose, shortness of breath, sore throat, stomach inflammation,
sweating.
The single large dose of Zithromax that is prescribed
to treat sexually transmitted infection of the cervix or urinary tract
is more likely to cause stomach and bowel side effects than the smaller
doses prescribed for a skin or respiratory tract infection.
Why should Zithromax not be prescribed ?
Do not take Zithromax if you have ever had an allergic
reaction to it or to similar antibiotics such as erythromycin (E.E.S.,
PCE, and others).
Special warnings about Zithromax
Like certain other antibiotics, Zithromax may cause a
potentially life-threatening form of diarrhea called pseudomembranous
colitis. Pseudomembranous colitis may clear up spontaneously when Zithromax
is stopped; if it doesn't, hospital treatment may be required. If you
develop diarrhea, check with your doctor immediately.
If you have a liver problem, your doctor should monitor
you very carefully while you are taking Zithromax.
Possible food and drug interactions when taking
Zithromax
Do not take Zithromax with antacids containing aluminum
or magnesium, such as Maalox and Mylanta.
If Zithromax is taken with certain other drugs, the effects
of either could be increased, decreased, or altered.
It is especially important to check with your
doctor before combining Zithromax with the following:
Nelfinavir (Viracept)
Warfarin (Coumadin)
Digoxin (Lanoxin, Lanoxicaps)
Ergot-containing drugs such as Cafergot and D.H.E.
Cyclosporine (Neoral and Sandimmune)
Hexobarbital
Phenytoin (Dilantin)
Special information if you are pregnant or breastfeeding
If you are pregnant or plan to become pregnant, inform your doctor immediately.
You should take Zithromax during pregnancy only if it is clearly needed.
It is not known whether Zithromax can make its way into breast milk. If
the drug is essential to your health, your doctor may advise you to stop
breastfeeding until your treatment of Zithromax is finished.
Recommended dosages for Zithromax
ADULTS
Respiratory Diseases, Tonsillitis, Strep Throat, and Skin Infections
The usual dose of Zithromax is 500 milligrams in a single dose the first
day. This is followed by 250 milligrams once daily for the next 4 days.
Alternatively, patients with chronic obstructive pulmonary disease may
be prescribed 500 milligrams a day for 3 days.
Genital Ulcer Disease
The usual dose is a single gram (1,000 milligrams) one time only.
Sexually Transmitted Diseases
The usual dose is a single 2-gram (2,000 milligrams) dose.
CHILDREN
Middle Ear Infection
For children aged 6 months and up, treatment may be given three ways.
One option is a single dose of 30 milligrams per 2.2 pounds of body weight.
Another option is a dose of 10 milligrams per 2.2 pounds given each day
for 3 days. Zithromax can also be given over a period of 5 days, starting
with a dose of 10 milligrams per 2.2 pounds on the first day and continuing
with daily doses of 5 milligrams per 2.2 pounds for the next 4 days.
Pneumonia
For children aged 6 months and up, the usual dose is 10 milligrams of
Zithromax suspension per 2.2 pounds of body weight in a single dose the
first day, followed by 5 milligrams per 2.2 pounds for the next 4 days.
Strep Throat and Tonsillitis
For children aged 2 years and up, the usual dose is 12 milligrams per
2.2 pounds of body weight once daily for 5 days.
Overdosage with Zithromax
Although no specific information on Zithromax overdose is available,
any medication taken in excess can have serious consequences. If you suspect
an overdose, seek medical attention immediately.
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