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Rabeprazole Sodium
Generic name: Rabeprazole Sodium
Brand names: Pariet, AcipHex

Rabeprazole Sodium blocks acid production in the stomach.
It is prescribed for the short-term (4 to 8 weeks) treatment of sores
and inflammation in the upper digestive canal (esophagus). This condition,
known as gastroesophageal reflux disease (GERD), is caused by the backflow
of stomach acid into the esophagus over a prolonged period of time. Because
GERD can be chronic, your doctor may continue to prescribe Rabeprazole
Sodium to prevent a relapse after your initial course of treatment and
to relieve symptoms of GERD such as heartburn. Rabeprazole Sodium can
also be prescribed for the short-term (up to 4 weeks) treatment of duodenal
ulcers (ulcers that form just outside the stomach at the top of the small
intestine), and for Zollinger-Ellison syndrome, a disease which causes
the stomach to produce too much acid. Rabeprazole Sodium is classified
as a "proton pump inhibitor." It works by blocking a specific
enzyme essential to the production of stomach acid. It begins reducing
acid within an hour of administration
Most important fact about Rabeprazole Sodium
Rabeprazole Sodium will work even if your symptoms are
caused by a serious condition such as stomach cancer. For that reason,
doctors are warned to rule out cancer whenever prescribing Rabeprazole
Sodium.
How should you take Rabeprazole Sodium ?
Take Rabeprazole Sodium once a day. Swallow the tablet
whole; it should not be crushed, chewed, or split. You can continue taking
antacids during Rabeprazole Sodium therapy.
If you miss a dose of Rabeprazole Sodium
Take it as soon as you remember. If it is almost time
for your next dose, skip the one you missed and go back to your regular
schedule. Do not take two doses at once.
Storage information for Rabeprazole Sodium
Rabeprazole Sodium should be stored at room temperature
and protected from moisture.
What side effects when taking Rabeprazole Sodium
may occur ?
Side effects cannot be anticipated. If any develop or
change in intensity, tell your doctor as soon as possible. Only your doctor
can determine if it is safe for you to continue taking Rabeprazole Sodium.
Headache is the most common side effect of Rabeprazole
Sodium, striking two people out of 100.
Less common side effects when taking Rabeprazole
Sodium may include:
Abdominal pain, abnormal dreams, abnormal stools, abnormal
vision, allergic reaction, anxiety, arthritis, asthma, belching, bladder
inflammation, bone pain, breakthrough menstrual bleeding, bruising, bursitis,
cataract, chest pain, chills, constipation, convulsion, decreased sex
drive, dehydration, depression, diarrhea, difficult breathing, difficult
periods, dizziness, dry eyes, dry mouth, ear infection, fainting, fatigue,
fever, fluid retention, frequent urination, gallbladder disease, gas,
glaucoma, gout, gum inflammation, hair loss, heart attack, hiccup, high
blood pressure, hives, hyperventilation, increased appetite, inflammation
of the esophagus, inflammation of the pancreas, insomnia, intestinal inflammation,
irregular heartbeat, itching, joint disease, kidney stone, laryngitis,
leg cramps, loss of appetite, lymph node disease, migraine, mouth inflammation,
mouth sores, muscle pain, nausea, nerve pain, nervous system disorder,
nervousness, nosebleed, overactive thyroid, painful urination, pins and
needles sensation, pounding heartbeat, rash, rectal bleeding or inflammation,
ringing in the ears, sensitivity to sunlight, sleepiness, slowed or racing
heartbeat, stiff neck, stiffness, stomach upset or inflammation, sweating,
tongue inflammation, tremor, underactive thyroid, vertigo, vomiting, weakness,
weight gain or loss.
Rare side effects when taking Rabeprazole Sodium
may include:
Abdominal swelling, absence of breathing, agitation, amnesia,
bile duct inflammation, blood clot, blood in the urine, blood vessel enlargement,
bloody diarrhea, breast enlargement, confusion, deafness, dry skin, eye
pain, fluid retention of the face, hangover effect, heavy periods, hyperactivity,
impotence, inflammation of the small intestine, intestinal bleeding, irregular
heartbeat, liver disorders, nervous disorders, salivary gland enlargement,
shingles, skin discoloration or scaling, slowed breathing, stomach bleeding,
testicular inflammation, thirst, twitching, urinary incontinence, vaginal
discharge, vein inflammation, visual disturbance.
Why should Rabeprazole Sodium not be prescribed
?
If Rabeprazole Sodium gives you an allergic reaction,
you will not be able to use it.
Special warnings about Rabeprazole Sodium
If you have stomach ulcers caused by the H. pylori bacteria,
Rabeprazole Sodium could make the condition slightly worse. The doctor
may order a test for H. pylori before prescribing Rabeprazole Sodium.
Rabeprazole Sodium has not been tested in children
under 18 years of age.
Possible food and drug interactions when taking
Rabeprazole Sodium
If AcipHex is taken with certain other drugs, the effects
of either could be increase, decreased, or altered.
It is especially important to check with your
doctor before combining Rabeprazole Sodium with the following:
Cyclosporine (Neoral, Sandimmune)
Digoxin (Lanoxin)
Ketoconazole (Nizoral)
Warfarin (Coumadin)
Special information if you are pregnant or breastfeeding
The effects of Rabeprazole Sodium during pregnancy have
not been adequately studied. If you are pregnant or plan to become pregnant,
inform your doctor immediately. Rabeprazole Sodium may appear in breast
milk and should not be taken while you're breastfeeding.
Recommended dosages for Rabeprazole Sodium
ADULTS
Gastroesophageal Reflux Disease (GERD)
The usual dose of Rabeprazole Sodium is 20 milligrams
once a day for 4 to 8 weeks. For patients who have not healed after 8
weeks, the doctor may prescribe an additional 8-week course of Rabeprazole
Sodium therapy.
To Relieve Symptoms or Prevent a Relapse of GERD
The usual dose is 20 milligrams once a day.
Duodenal Ulcer
The usual dose is 20 milligrams taken once daily after
the morning meal for a period of up to 4 weeks. Some people may require
an additional 4 weeks of treatment of Rabeprazole Sodium.
Zollinger-Ellison Syndrome
The usual starting dose is 60 milligrams once a day, although
your doctor may adjust the dose based on your individual need. Doses of
up to 100 milligrams once a day or 60 milligrams twice a day are sometimes
prescribed.
Overdosage with AcipHex
Little is known about Rabeprazole Sodium overdose. However,
any medication taken in excess can have serious consequences. If you suspect
an overdose of Rabeprazole Sodium, seek medical attention immediately.
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