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Protonix
Generic name: Pantoprazole Sodium
Brand names: Pantecta, Protonix

Protonix blocks the production of stomach acid. It is
prescribed to heal a condition called erosive esophagitis (a severe inflammation
of the passage to the stomach) brought on by a persistent backflow of
stomach acid (gastroesophageal reflux disease). Later, it may be prescribed
to maintain healing and prevent a relapse. It is also used in the treatment
of conditions marked by constant overproduction of stomach acid, such
as Zollinger-Ellison Syndrome. Protonix is a member of the "proton
pump inhibitor" class of acid blockers, which includes AcipHex, Nexium,
Prilosec, and Prevacid
Most important fact about Protonix
Protonix is highly effective. In most patients, stomach
acid secretion drops 85 to 95 percent after a single week of treatment.
How should you take Protonix ?
Protonix may be taken with or without food. Do not chew,
crush, or split the delayed-release tablets. If you are taking antacids
you may continue to do so.
If you miss a dose of Protonix
Take Protonix as soon as you remember. If it is almost
time for your next dose, skip the one you missed and go back to your regular
schedule. Never take two doses at once.
Storage instructions for Protonix
Store Protonix at room temperature.
What side effects when taking Protonix may occur
?
Side effects with Protonix cannot be anticipated. If any
develop or change in intensity, tell your doctor as soon as possible.
Only your doctor can determine if it is safe for you to continue taking
Protonix.
More common side effects when taking Protonix
may include:
Diarrhea, headache
Less common side effects when taking Protonix
may include:
Abdominal pain, burping, gas, nausea, vomiting
Rare side effects when taking Protonix may include:
Insomnia, rash
Why should Protonix not be prescribed ?
If Protonix gives you an allergic reaction, you'll be
unable to use it.
Special warnings about Protonix
Protonix has been proven safe and effective for periods
of up to 16 weeks, but hasn't been tested for longer periods and isn't
currently recommended for long-term use.
Protonix has been known to cause several extremely rare,but
very serious,side effects, including severe allergic reaction, severe
swelling of the face and throat, eye damage, dangerous skin reactions,
and inflammation of the pancreas. Seek emergency care immediately if you
begin to have difficulty breathing or swallowing, or begin to develop
blisters, eruptions, or peeling skin.
If you have a liver condition, make sure the doctor is
aware of it. A dosage adjustmentof Protonix may be needed for anyone with
serious liver disease.
Protonix has not been tested for safety or effectiveness
in children.
Possible food and drug interactions when taking
Protonix
If Protonix is taken with certain other drugs, the effects
of either could be increased, decreased, or altered.
It is especially important to check with your
doctor before combining Protonix with the following:
Ampicillin (Omnipen)
Iron
Ketoconazole (Nizoral)
Special information if you are pregnant or breastfeeding
Although no harmful effects during pregnancy are known with Protonix
, there's no definite proof of safety either. Protonix is therefore recommended
during pregnancy only if clearly needed. If you are pregnant or plan to
become pregnant, inform your doctor immediately. There is a possibility
that Protonix may appear in breast milk, causing serious side effects
in the nursing infant. If you have to take Protonix, you should not plan
on breastfeeding.
Recommended dosages for Protonix
ADULTS
Erosive Esophagitis
The usual dose of Protonix is 40 milligrams once a day for up to 8 weeks.
If your esophagus hasn't healed in that time, your doctor may prescribe
an additional 8-week course of therapy. The same dose is used to maintain
healing.
Overproduction of Stomach Acid
The usual starting dose is 40 milligrams twice a day. The doctor may
increase the dose if necessary. Doses as high as 240 milligrams per day
have been used. Treatment may continue for years.
Overdosage with Protonix
Any medication taken in excess can have serious consequences. Although
little is known about Protonix overdose in humans, in animal studies it
interferes with coordination and reduces activity. If you suspect an overdose
of Protonix, seek medical attention immediately.
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