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Neurontin
Generic name: Gabapentin
Neurontin has two uses. First, it may be prescribed with
other medications to treat partial seizures (the type in which symptoms
are limited). It can be used whether or not the seizures eventually become
general and result in loss of consciousness. Second, it can be used to
relieve the burning nerve pain that sometimes persists for months or even
years after an attack of shingles (herpes zoster)
Most important fact about Neurontin
Take Neurontin exactly as directed by your doctor. To
effectively control your seizures, it is important that you take Neurontin
3 times a day, approximately every 8 hours. You should not go longer than
12 hours without a dose of Neurontin.
How should you take Neurontin ?
Do not increase or decrease dosage of Neurontin without
your doctor's approval; and do not suddenly stop taking it, as this may
cause an increase in the frequency of your seizures. If you are taking
an antacid such as Maalox, take Neurontin at least 2 hours after the antacid.
You may take Neurontin with or without food.
If you miss a dose of Neurontin
Try not to allow more than 12 hours to pass between doses.
Do not double doses.
Storage instructions for Neurontin
Store capsules and tablets at room temperature. Keep the
oral solution refrigerated.
What side effects when taking Neurontin may occur
?
Side effects cannot be anticipated. If any develop or
change in intensity, inform your doctor as soon as possible. Only your
doctor can determine if it is safe for you to continue taking Neurontin.
When taken for epilepsy, more common side effects
when taking Neurontin may include:
Blurred, dimmed, or double vision, bronchitis (in children), dizziness,
drowsiness, fatigue, fever (in children), involuntary eye movement, itchy,
runny nose, lack of muscular coordination, nausea, tremor, viral infection
(in children), vomiting, weight increase (in children)
When taken for nerve pain, more common side effects
when taking Neurontin may include:
Accidental injury, constipation, diarrhea, dizziness,
drowsiness, dry mouth, headache, infection, lack of muscular coordination,
nausea, swelling in arms and legs, vomiting, weakness
A wide variety of uncommon and rare side effects have
also been reported. If you develop any new or unusual symptoms while taking
Neurontin, be sure to let your doctor know.
Why should Neurontin not be prescribed ?
You should not take Neurontin if you have ever had an
allergic reaction to it.
Special warnings about Neurontin
Neurontin causes some people to become drowsy and less
alert. Combining it with morphine makes this more likely. Do not drive
or operate dangerous machinery or participate in any hazardous activity
that requires full mental alertness until you are certain Neurontin does
not have this effect on you.
In children, Neurontin occasionally triggers behavioral
problems such as unstable emotions, hostility, aggression, hyperactivity,
and lack of concentration. However, such problems (if they occur) are
usually mild.
Be sure to tell your doctor if you have any kidney problems
or are on hemodialysis, as your doctor will need to adjust your dosage
of Neurontin.
Tell your doctor about any medications you are taking,
including over-the-counter drugs.
Possible food and drug interactions when taking
Neurontin
If Neurontin is taken with certain other drugs, the effects
of either can be increased, decreased, or altered.
It is especially important to check with your
doctor before combining Neurontin with the following:
Antacids such as Maalox
Hydrocodone (Lortab, Vicodin)
Naproxen (Naprosyn)
Morphine (Kadian, MS Contin)
Special information if you are pregnant or breastfeeding
The effects of Neurontin on pregnant women have not been
adequately studied, although birth defects have occurred in babies whose
mothers took an antiepileptic medication while they were pregnant. Neurontin
should be used during pregnancy only if clearly needed. If you are pregnant
or plan to become pregnant, tell your doctor immediately. Neurontin may
appear in breast milk and could affect a nursing infant. It should be
used by mothers who nurse their babies only if its benefits clearly outweigh
the risks.
Recommended dosages for Neurontin
EPILEPSY
Adults and Children 12 Years and Over
The recommended starting dose is 300 milligrams three
times a day. After that, the usual daily dosage ranges from 900 to 1,800
milligrams divided into 3 doses.
If Neurontin is discontinued or another drug is added
to therapy, your doctor will do this gradually, over a 1-week period.
Children 3 to 12 Years of Age
Daily dosage is calculated according to the child's weight.
The usual starting dosage is 10 to 15 milligrams per 2.2 pounds. Dosage
is then increased over a period of three days to 40 milligrams per 2.2
pounds for children aged 3 and 4, and 25 to 35 milligrams per 2.2 pounds
for children aged 5 and over. The total daily dosage is taken as 3 smaller
doses throughout the day.
PAIN FOLLOWING A SHINGLES ATTACK
Treatment typically starts with a single 300-milligram
dose on the first day, two 300-milligram doses on the second day, and
three 300-milligram doses on the third day. If necessary, the doctor may
increase the daily total to as much as 1,800 milligrams, divided into
three doses.
Whether you are taking Neurontin for epilepsy or pain,
the doctor will adjust the dosage downward if you have poor kidney function.
Overdosage with Neurontin
Any medication taken in excess can have serious consequences.
If you suspect an overdose of Neurontin, seek medical treatment immediately.
Symptoms of Neurontin overdose may include:
Diarrhea, double vision, drowsiness, lethargy, slurred speech
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