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Brand name: Flagyl
Generic name: Metronidazole
Metronidazole is an antibacterial drug prescribed for
certain vaginal and urinary tract infections in men and women; amebic
dysentery and liver abscess; and infections of the abdomen, skin, bones
and joints, brain, lungs, and heart caused by certain bacteria
Metronidazole 400mg
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Metronidazole 200mg
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Most important fact about Metronidazole
Do not drink alcoholic beverages while taking Metronidazole.
The combination can cause abdominal cramps, nausea, vomiting, headaches,
and flushing. It can also change the taste of the alcoholic beverage.
When you have stopped taking Metronidazole, wait at least 72 hours (3
days) before consuming any alcohol. Also avoid over-the-counter medications
containing alcohol, such as certain cough and cold products.
How should you take Metronidazole?
Metronidazole works best when there is a constant amount
in the blood. Take your doses at evenly spaced intervals, day and night,
and try to avoid missing any. If you are being treated for the sexually
transmitted genital infection called trichomoniasis, your doctor may want
to treat your partner at the same time, even if there are no symptoms.
Try to avoid sexual intercourse until the infection is cured. If you do
have sex, use a condom.
Metronidazole can be taken with or without food. It may
cause dry mouth. Hard candy, chewing gum, or bits of ice can help to relieve
the problem.
If you miss a dose of Metronidazole
Take Metronidazole as soon as you remember. If it is almost
time for your next dose skip the one you missed and go back to your regular
schedule. Do not take 2 doses at once.
Storage instructions for Metronidazole
Store at room temperature. Protect from light.
What side effects when taking Metronidazole may
occur ?
Side effects of Metronidazole cannot be anticipated. If
any develop or change in intensity, tell your doctor immediately. Only
your doctor can determine whether it is safe for you to continue taking
Metronidazole.
Two serious side effects that have occurred with Metronidazole
are seizures and numbness or tingling in the arms, legs, hands, and feet.
If you experience either of these symptoms, stop taking Metronidazole
and call your doctor immediately.
More common side effects when taking Metronidazole
may include:
Abdominal cramps, constipation, diarrhea, headache, loss
of appetite, nausea, upset stomach, vomiting
Less common side effects when taking Metronidazole
may include:
Blood disorders, confusion, dark urine, decreased sex
drive, depression, difficulty sleeping, dizziness, dry mouth (or vagina
or vulva), fever, flushing, furry tongue, hives, inability to hold urine,
increased production of pale urine, inflamed mouth or tongue, inflammation
of the rectum, irritability, lack of muscle coordination, metallic taste,
occasional joint pain, pain during sexual intercourse, painful or difficult
urination, pelvic pressure, rash, stuffy nose, vertigo, weakness, yeast
infection (candida) in vagina.
Why should Metronidazole not be prescribed ?
Metronidazole should not be used during the first 3 months
of pregnancy to treat vaginal infections. Do not take Metronidazole if
you have ever had an allergic reaction to or are sensitive to metronidazole
or similar drugs. Tell your doctor about any drug reactions you have experienced.
Special warnings about Metronidazole
If you experience seizures or numbness or tingling in
your arms, legs, hands, or feet, remember that you should stop taking
Metronidazole and call your doctor immediately.
If you have liver disease, make sure the doctor is aware
of it. Metronidazole should be used with caution.
Active or undiagnosed yeast infections may appear or worsen
when you take Metronidazole.
Possible food and drug interactions when taking
Metronidazole
Do not drink alcohol while taking Metronidazole and for
at least 72 hours after your last dose.
If Metronidazole is taken with certain other drugs, the
effects of either could be increased, decreased, or altered.
It is especially important to check with your
doctor before combining Metronidazole with any of the following:
Blood thinners such as Coumadin
Cholestyramine (Questran)
Cimetidine (Tagamet)
Disulfiram (Antabuse)
Lithium (Eskalith)
Phenobarbital
Phenytoin (Dilantin)
Special information if you are pregnant or breastfeeding
The effects of Metronidazole in pregnancy have not been
adequately studied. If you are pregnant or plan to become pregnant, notify
your doctor.Metronidazole should be used during pregnancy only if it is
clearly needed. Metronidazole appears in breast milk and could affect
a nursing infant. If Metronidazole is essential to your health, your doctor
may advise you to stop breastfeeding until your treatment of Metronidazole
finished.
Recommended dosages for Metronidazole
ADULT
Trichomoniasis
One-day treatment: 2 grams of Metronidazolel, taken as
a single dose or divided into 2 doses (1 gram each) taken in the same
day.
Seven-day course of treatment: 250 milligrams 3 times
daily for 7 consecutive days.
Acute Intestinal Amebiasis (Acute Amebic Dysentery)
The usual dose is 750 milligrams taken by mouth 3 times
daily for 5 to 10 days.
Amebic Liver Abscess
The usual dose is 500 milligrams or 750 milligrams taken
by mouth 3 times daily for 5 to 10 days.
Anaerobic Bacterial Infections
The usual adult oral dosage is 7.5 milligrams per 2.2
pounds of body weight every 6 hours.
CHILDREN
Amebiasis
The usual dose is 35 to 50 milligrams for each 2.2 pounds
of body weight per day, divided into 3 doses taken for 10 days.
The safety and efficacy of Metronidazole for any other
condition in children have not been established.
OLDER ADULTS
Your doctor will test to see how much Metronidazole is
in your blood and will adjust your dosage if necessary.
Overdosage with Metronidazole
Any medication taken in excess can have serious consequences.
If you suspect an overdose of Metronidazole, seek medical treatment immediately.
Symptoms of Metronidazole overdose may include:
Lack of muscle coordination, nausea, vomiting
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