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Doxazosin

Brand names: Cardura, Carduran Neo

Generic name: Doxazosin Mesylate

Doxazosin is used in the treatment of benign prostatic hyperplasia, a condition in which the prostate gland grows larger, pressing on the urethra and threatening to block the flow of urine from the bladder. Doxazosin relieves symptoms such as a weak stream, dribbling, incomplete emptying of the bladder, frequent urination, and burning during urination. Doxazosin is also used in the treatment of high blood pressure. It is effective when used alone or in combination with other blood pressure medications, such as diuretics, beta-blocking medications, calcium channel blockers or ACE inhibitors. Doctors also prescribe Doxazosin, along with other drugs such as digitalis and diuretics, for treatment of congestive heart failure

Most important fact about Doxazosin

If you have high blood pressure, you must take Doxazosin regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Doxazosin; and you must continue taking it even if you are feeling well.Doxazosina does not cure high blood pressure; it merely keeps it under control.

How should you take Doxazosin ?

Doxazosin can be taken with or without food.

Doxazosin should be taken exactly as prescribed, even if your symptoms have disappeared. Try not to miss any doses. IfDoxazosin is not taken regularly, your condition may worsen.

If you have benign prostatic hyperplasia, you should see improvement in a week. Blood pressure will fall in 2 to 6 hours.

If you miss a dose of Doxazosin

Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time.

Storage instructions for Doxazosin

Store at room temperature.

What side effects when taking Doxazosin may occur ?

Side effects of Doxazosin cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Doxazosin.

More common side effects when taking Doxazosin may include:

Dizziness, drowsiness, fatigue, headache

Less common side effects when taking Doxazosin may include:

Abdominal pain, abnormal vision, arthritis, constipation, depression, diarrhea, difficulty sleeping, dry mouth, eye pain, fluid retention, flu-like symptoms, flushing, gas, increased sweating, inability to hold urine or other urination problems, indigestion, inflammation of conjunctiva (pinkeye), itching, flushes, joint pain, lack of muscle coordination, low blood pressure, motion disorders, muscle cramps, muscle pain, muscle weakness, nasal stuffiness, nausea, nervousness, nosebleeds, pain, rash, ringing in ears, shortness of breath, thirst, tingling or pins and needles, weakness.

Rare side effects when taking Doxazosin may include:

Abnormal thinking, agitation, allergic reactions, altered sense of smell, amnesia, blood in the urine, breast development in men, breast pain, breathing difficulties, changeable emotions, changes in taste, chest pain, confusion, coughing, decreased sensation, dizziness when standing up, dry skin, earache, fainting, fecal incontinence, fever, frequent urination, gout, hair loss, heart attack, hives, inability to concentrate, inability to tolerate light, increased appetite, increased thirst, infection, loss of appetite, loss of sense of personal identity, migraine headache, morbid dreams, nighttime urination, pallor, prolonged erections, rapid pounding heartbeat, sexual problems, sinus inflammation, slight or partial paralysis, slow heartbeat, sore throat, stroke, tremors, twitching, urinary disorders, vomiting, weight gain, weight loss, wheezing, yellow skin and eyes.

Why should Doxazosin not be prescribed ?

Doxazosin should not be taken if you are sensitive to or have ever had an allergic reaction to Doxazosin or such drugs as Minipress or Hytrin. Make sure your doctor is aware of any drug reactions you may have experienced.

Special warnings about Doxazosin

Doxazosin can cause low blood pressure, especially when you first start taking Doxazosin and when dosage is increased. This can cause you to become faint, dizzy, or light-headed, particularly when first standing up. You should avoid driving or any hazardous tasks where injury could occur for 24 hours after taking the first dose, after your dose has been increased, or if Doxazosin has been stopped and then restarted.

In rare cases, men taking drugs such asDoxazosin have developed priapism - a painful, long-lasting erection that persists for hours. This condition can lead to impotence, so if it occurs contact your doctor right away.

If you have liver disease or are taking other medications that alter liver function, your doctor will monitor you closely when you take Doxazosin.

Doxazosin may lower blood counts. Your doctor will most likely monitor your blood counts while you are taking Doxazosin.

Doxazosin may cause you to become drowsy or sleepy. For this reason, too, driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness is not recommended.

Prostate cancer has some of the same symptoms as benign prostatic hyperplasia; your doctor will want to make sure you do not have cancer before starting you on Doxazosin.

Possible food and drug interactions when taking Doxazosin

No significant interactions have been reported.

Special information if you are pregnant or breastfeeding

The effects of Doxazosin during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Doxazosin may appear in breast milk and could affect a nursing infant. If Doxazosin is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Doxazosin is finished.

Recommended dosages for Doxazosin

ADULTS

Your doctor will adjust the dosage to fit your needs. The usual starting dose is 1 milligram taken once a day. To minimize the potential for dizziness or fainting associated with Cardura, which may occur between 2 and 6 hours after a dose, your doctor will monitor your blood pressure during this period and afterwards.

After the effects of the starting dose are measured, your doctor may increase the daily dose to 2 milligrams and then, if necessary, to 4 milligrams, 8 milligrams, or, in people with high blood pressure only, up to 16 milligrams. As the dose increases, the potential for side effects such as dizziness, vertigo, light-headedness, and fainting also increases.

CHILDREN

The safety and effectiveness of Doxazosin in children have not been established.

Overdosage with Doxazosin

Any medication taken in excess can have serious consequences. Although no specific information is available, low blood pressure is the most likely symptom of an overdose of Doxazosin..

If you suspect an overdose of Doxazosin, seek medical attention immediately.