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Information about Cialis and how the tablets work and take effect
Cialis acts in the same way as Viagra, by blocking an enzyme
called phosphodiesterase-5, or PDE-5. This helps the smooth muscles in the
penis relax and widen, which allows for more blood to enter. As a result,
you gain erections faster and easier with Cialis. Cialis is a treatment
for men with erectile dysfunction. This is when a man cannot get, or can
not keep a hard erect penis needed for sexual activity to please his partner.
Cialis does not work if there is no sexual stimulation. You and your partner
will need to engage in foreplay first as you would naturally if you were
not taking a medicine for erectile dysfunction.
How well does Cialis work ?
Cialis test results showed that out of 700 participants,
at least 88% of men experienced improvement with their erections and were
able to acheive erections from 12-24 hours after they take Cialis.
Cialis doseages
In Cialis clinical testing most men were administered one 10 mg Cialis
or 20 mg Cialis tablet per day.
Use in Adult Men
The recommended dose of Cialis is 20 mg, taken prior to anticipated sexual
activity. The maximum recommended dosing frequency is once per day. Cialis
may be taken between 30 minutes and 36 hours prior to anticipated sexual
activity. Patients may initiate sexual activity at varying time points
relative to dosing in order to determine their own optimal window of responsiveness.
The dose may be lowered to 10 mg based on individual response and tolerability.
Cialis may be taken without regard to food.
Use in Elderly Men
Cialis dosage adjustments are not required in elderly patients. Dosage
recommendations described in - Use in adult men - apply to elderly men.
Use in Men with Impaired Renal Function
Dosage adjustments are not required in patients with renal impairment.
Use in Men with Impaired Hepatic Function
Dosage adjustments are not required in patients with mild to moderate
hepatic impairment (Child-Pugh Class A and B) (see Pharmacokinetics).
Use in men with diabetes
The presence of diabetes does not require a dose reduction.
Use in children
Cialis should not be used in individuals below 18 years of age.
Side effects of Cialis
The most common side effects reported with Cialis in the study were headache,
myalgia (muscle pain), dyspepsia (upset stomach following meals) and back
pain. The severities of these Cialis side effects were minimized with
lower doses of Cialis.
Warnings and Precautions of Cialis
Sexual activity carries a potential cardiac risk for patients with pre-existing
cardiovascular disease. Therefore, treatments for erectile dysfunction,
including Cialis, should not be used in men with cardiac disease for whom
sexual activity is inadvisable. Physicians should consider the potential
cardiac risk of sexual activity in patients with pre-existing cardiovascular
disease.
Effects on Ability to Drive and Use Machines
Although the frequency of reports of dizziness in placebo and tadalafil
arms in clinical trials was similar, patients should be aware of how they
react to Cialis, before driving or operating machinery.
Adverse Effects of Cialis
Cialis was administered to over 4000 subjects (aged 19 to 86 years) during
clinical trials worldwide. Over 230 patients were treated for longer than
one year and over 720 patients were treated for over 6 months. In controlled
phase 2/3 clinical trials, the discontinuation rate due to adverse effects
in Cialis-treated patients (1.7%) was not significantly different from
placebo-treated patients (1.1%). In these studies, the adverse effects
reported with Cialis were generally mild or moderate, transient, and decreased
with continued dosing.
Overdosage of Cialis
Single doses of up to 500 mg of Cialis have been given to healthy subjects,
and multiple daily doses up to 100 mg have been given to patients. Adverse
events were similar to those seen at lower doses. In cases of an overdose
of Cialis, standard supportive measures should be adopted as required.
Storage of Cialis
Store below 25°C. Store in the original package.
Handling instructions on Cialis
No special requirements.
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