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Celexa
Generic name: Citalopram hydrobromide
Celexa is used to treat major depression--a
stubbornly low mood that persists nearly every day for at least 2 weeks
and interferes with everyday living. Symptoms may include loss of interest
in your usual activities, insomnia or excessive sleeping, a change in
weight or appetite, constant fidgeting or a slowdown in movement, fatigue,
feelings of worthlessness or guilt, difficulty thinking or concentrating,
and repeated thoughts of suicide.
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Like the antidepressant medications Paxil,
Prozac, and Zoloft, Celexa is thought to work by boosting serotonin
levels in the brain. Serotonin, one of the nervous system's primary
chemical messengers, is known to elevate mood
Most important fact about Celexa
Be careful to avoid taking Celexa for 2
weeks before or after using an antidepressant known as an MAO inhibitor.
Drugs in this category include Marplan, Nardil, and Parnate. Combining
Celexa with one of these medications could lead to a serious--even fatal--reaction.
How should you take Celexa ?
Celexa is available in tablet and liquid
forms. Take either formulation once a day, in the morning or evening,
with or without food. Although your depression will begin to lift in
1 to 4 weeks, you should continue taking Celexa regularly. It takes
several months for the medication to yield its full benefits.
If you miss a dose of Celexa
Take it as soon as you remember. If it
is almost time for your next dose, skip the one you missed and go back
to your regular schedule. Do not take 2 doses at the same time.
Storage instructions for Celexa
Store at room temperature.
What side effects may occur by
taking Celexa ?
Side effects cannot be anticipated. If
any develop or change in intensity, inform your doctor as soon as possible.
Only your doctor can determine if it is safe for you to continue taking
Celexa.
More common side effects may include:
Abdominal pain, agitation, anxiety, diarrhea, drowsiness, dry mouth,
ejaculation disorders, fatigue, impotence, indigestion, insomnia, loss
of appetite, nausea, painful menstruation, respiratory tract infection,
sinus or nasal inflammation, sweating, tremor, vomiting
Less common side effects may include:
Amnesia, attempted suicide, confusion, coughing, decreased sexual drive,
depression, excessive urination, fever, gas, impaired concentration,
increased appetite, increased salivation, itching, joint pain, lack
of emotion, loss of menstruation, low blood pressure, migraine, muscle
pain, rapid heartbeat, rash, skin tingling, taste disturbances, visual
disturbances, weight gain, weight loss, yawning
Rare side effects may include:
Abnormal dreams, acne, aggressive behavior, alcohol intolerance, angina
(chest pain), arthritis, belching, bone pain, breast enlargement, breast
pain, bronchitis, bruising, chills, conjunctivitis (pinkeye), decreased
muscle movements, delusions, dermatitis, difficulty breathing, difficulty
swallowing, dizziness, drug dependence, dry eyes, dry skin, eczema,
emotional instability, excessive milk flow, excessive muscle tone, eye
pain, fainting, feeling of well-being, flu-like symptoms, flushing,
frequent urination, gum inflammation, hair loss, hallucinations, heart
attack, heart failure, hemorrhoids, high blood pressure, hives, hot
flashes, inability to hold urine, inability to urinate completely, increased
sex drive, increased urination, involuntary muscle movements, leg cramps,
mouth sores, muscle weakness, nosebleeds, numbness, painful erection,
painful urination, panic, paranoia, pneumonia, psoriasis, psychosis,
ringing in the ears, sensitivity to light, skin discoloration, slow
heartbeat, stomach and intestinal inflammation, stroke, swelling, teeth
grinding, thirst, uncontrollable muscle movements, unsteady or abnormal
walk, vaginal bleeding
Why should Celexa not be prescribed
?
If Celexa gives you an allergic reaction,
you cannot continue using it. Also remember that Celexa must never be
combined with an MAO inhibitor (see "Most important fact about
this drug," above).
Special warnings about Celexa
In recommended doses, Celexa does not seem
to impair judgment or motor skills. However, a theoretical possibility
of such problems remains, so you should use caution when driving or
operating dangerous equipment until you are certain of Celexa's effect.
There is a slight chance that Celexa will
trigger a manic episode. Use Celexa with caution if you suffer from
manic-depression (bipolar disorder). Use caution, too, if you are over
60 years old, have liver or kidney problems, suffer from heart disease
or high blood pressure, or have ever had seizures.
Possible food and drug interactions
when taking Celexa
Celexa does not increase the effects of
alcohol. Nevertheless, it's considered unwise to combine Celexa with
alcohol or any other drug that affects the brain. (Be particularly careful
to avoid MAO inhibitors.)
If Celexa is taken with certain other drugs,
the effects of either could be increased, decreased, or altered. Tell
your doctor about any prescription or over-the-counter drugs you are
planning to take, and be especially certain to check with him before
combining Celexa with the following:
Carbamazepine (Tegretol)
Cimetidine (Tagamet)
Erythromycin (Eryc, Ery-Tab)
Fluconazole (Diflucan)
Itraconazole (Sporanox)
Ketoconazole (Nizoral)
Lithium (Lithobid, Lithonate)
Metoprolol (Lopressor)
Omeprazole (Prilosec)
Other antidepressants such as Elavil, Norpramin, Pamelor, and Tofranil
Sumatriptan (Imitrex)
Warfarin (Coumadin)
Special information if you are
pregnant or breastfeeding
The effects of Celexa during pregnancy
have not been adequately studied, and the potential for harm has not
been ruled out. If you are pregnant or plan to become pregnant while
on Celexa therapy, tell your doctor immediately.
Celexa appears in breast milk and will
affect the nursing infant. You should consider discontinuing either
breastfeeding or Celexa. Talk with your doctor about the pros and cons
of each option.
Recommended dosages of Celexa
ADULTS
The recommended starting dose of Celexa
tablets or oral solution is 20 milligrams once a day. Dosage is usually
increased to 40 milligrams once daily after at least a week has passed.
Do not exceed 40 milligrams a day.
For older adults and those who have liver problems, the recommended
dose is 20 milligrams once a day.
Overdosage
Any medication taken in excess can have
serious consequences. If you suspect an overdose, seek medical attention
immediately.
Symptoms of Celexa overdose may
include:
Amnesia, bluish or purplish discoloration of the skin, coma, confusion,
convulsions, dizziness, drowsiness, hyperventilation, nausea, rapid
heartbeat, sweating, tremor, vomiting
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