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Arimidex

Generic name: Anastrozole

Arimidex is a first-line treatment of breast cancer in postmenopausal women. It slows the growth of advanced cancer within the breast and cancer that has spread to other parts of the body. Arimidex is also used to treat advanced breast cancer in postmenopausal women whose disease has spread to other parts of the body following treatment with tamoxifen (Nolvadex), another anticancer drug. Arimidex can also be prescribed along with other drugs to treat the early stages of breast cancer in postmenopausal women. Arimidex combats the kind of breast cancer that thrives on estrogen. One of the hormones produced by the adrenal gland is converted to a form of estrogen by an enzyme called aromatase. Arimidex suppresses this enzyme and thereby reduces the level of estrogen circulating in the body

Most important fact about Arimidex

Arimidex, like many other anticancer medications, may prolong survival and improve quality of life. To keep Arimidex working properly, it's important to continue taking it even when you don't feel well. If you develop bothersome side effects, call your doctor. He or she can recommend ways to reduce your discomfort.

How should you take Arimidex ?

Take Arimidex exactly as directed.

If you miss a dose of Arimidex

Take the forgotten dose of Arimidex if you remember within 12 hours. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

Storage instructions for Arimidex

Store at room temperature.

What side effects when taking Arimidex may occur ?

Side effects cannot be anticipated with Arimidex. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Arimidex.

More common side effects when taking Arimidex may include:

Abdominal pain, accidental injury, anxiety, arthritis, back pain, bone pain, breast pain, cataracts, chest pain, constipation, cough, depression, diarrhea, dizziness, dry mouth, flu-like symptoms, fractures, headache, heart disease, high blood pressure or cholesterol, hot flashes, infection, insomnia, joint disease or pain, loss of appetite, nausea, osteoporosis, pain, pelvic pain and stiffness, "pins and needles," rash, shortness of breath, sore throat, stomach and intestinal upset, sweating, swelling of arms and legs, urinary tract infection, vaginal discharge or inflammation, vomiting, weakness, weight gain.

Less common or rare side effects when taking Arimidex may include:

Blood clots, bronchitis, confusion, drowsiness, feeling of illness, fever, hair thinning, heart attack, increased appetite, itching, muscle pain, nasal or sinus inflammation, neck pain, nervousness, severe blisters in the mouth or other mucous membranes, sluggishness, stroke, temporary tumor growth, tense muscles, vaginal bleeding, vaginal dryness, weight loss.

Why should Arimidex not be prescribed ?

Do not take Arimidex if you are pregnant or if you have an allergic reaction to Arimidex.

Special warnings about Arimidex

Because Arimidex may raise the level of cholesterol in your blood, your doctor may periodically do blood tests to check.

Possible food and drug interactions when taking Arimidex

Certain drugs may decrease the effectiveness of Arimidex, including tamoxifen (Nolvadex) and estrogen-containing drugs. Be sure to tell your doctor about any medication you are taking.

Special information if you are pregnant or breastfeeding

If you are pregnant or plan to become pregnant, do not take Arimidex. In animal studies, Arimidex has caused severe birth defects, including incomplete bone formation and low birth weight; it could be poisonous to your unborn child. Arimidex also increases your chances of having a miscarriage or a stillborn baby. If you should accidentally become pregnant, tell your doctor immediately. Because of the possibility of Arimidex passing through your breast milk to your baby, you should probably avoid breastfeeding.

Recommended dosages for Arimidex

ADULTS

The usual dose is a 1-milligram tablet taken once a day. If Arimidex is being used as an initial treatment for advanced breast cancer, you will continue taking Arimidex until it no longer works against the tumor. The optimal duration of therapy for early breast cancer has not been determined.

Overdosage with Arimidex

Although there have been no reports of Arimidex overdose, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.